Titles for all types of Cochrane Reviews should be in sentence case. Avoid the use of abbreviations (except for those listed as common abbreviations that do not need to be defined, see Abbreviations and acronyms), and avoid superfluous elements (e.g. ‘effects of’, ‘comparison of’, ‘a systematic review of’).
Titles can include italics (see section on Character formatting) but no other formatting.
Titles do not have a full-stop at the end.
Guidance on the structure of titles for Cochrane Reviews of interventions is included in the Cochrane Handbook for Systematic Reviews of Interventions.