Geographical Group Reporting Submission

Group Cochrane Madrid (IRYCIS/Universidad Francisco de Vitoria)

Name Jesús Lopez-Alcalde

Activity name / title Published Prognosis Factor Non-Cochrane Systematic Review: CD4/CD8 ratio and CD8+ T-cell count as prognostic markers for non-AIDS mortality in people living with HIV. A systematic review and meta-analysis

Which function does this relate to?

Tier one N/A

Tier two N/A

Tier three N/A

Tier four N/A

Evidence production Other review and evidence production

Date

Start date 01-02-2024

Proposed end date 01-02-2024

on-going No

Was this activity in collaboration with other organization(s) or partner(s)? If so which? Yes

Name of the organization(s) or partner(s) Department of Infectious Diseases, Hospital Universitario Ramón y Cajal and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain

Person to contact if any queries about this activity Jesus Lopez-Alcalde
cochrane.madrid@ufv.es

Type of activity Evidence production

Please give additional activity details (i.e., reach, impact, duration, return on investment) Our results support the use of the CD4/CD8 ratio as a prognostic marker in clinical practice, especially in patients with values below 0.5, but consensus criteria on ratio timing measurement, cut-off values, and time to event are needed in future studies to get more robust conclusions.

Link and documents

Link Published article

By checking this box, my center consents to the use of these photos for Cochrane internal and external purposes, such as websites, reports, social media, etc. No